Cancer Bone Metastases & Skeletal Related Events
Bone resorption related complications are the most common metabolic complications associated with cancers, and most of these are grouped as skeletal related events (SREs). SREs are most commonly associated with bone metastases. They encompass all the bone related outcomes including bone fractures, spinal cord compression and bone pain. Bone metastases are the most common site of metastases for cancers, and detected in 75% of all metastatic cancers . The US incidence of bone metastases is 400,000  and the global incidence is 1.5M .
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