Vancouver, British Columbia, March 27, 2017 – Altum Pharmaceuticals Inc. (“Altum” or the “Company”), a biopharmaceutical company engaged in clinical and commercial development of novel pharmaceutical compounds to treat cancer and autoimmune disorders, announces today it has signed an exclusive worldwide license agreement (ex certain eastern EU countries) with Altum-Avro Pharma Partnership (AAPP) for its late-stage, Biphasix™ technology platform, including the lead product candidate, interferon alpha 2b which has shown positive Phase II results in the treatment of HPV . Altum will be responsible for the continued clinical development and subsequent commercialization of the product for the treatment of HPV-induced, low-grade, cervical intraepithelial lesions (CIN). The market for the treatment of HPV-induced CIN is estimated to be in excess of $10 billion.

AAPP acquired the Biphasix™ technology platform and lead product topical interferon alpha 2b from Xisle Ventures Pharma trust which acquired the assets from Helix Biopharma.

Under the terms of the agreement, Altum agreed to; a) certain consideration to AAPP related to the sale of the inventory once the product is commercialized and; b) to milestone and royalty payments to Helix Biopharma as outlined in the original agreement between Xisle and Helix.
“Altum has achieved an important milestone in acquiring the exclusive licence to develop the topical interferon alpha 2b which had positive results in 2 Phase II clinical trials to treat cervical Intra-epithelial Neoplasia. Altum will now focus on conducting Phase III trials to develop the product for the treatment of potentially precancerous, low-grade cervical lesions caused by human papillomavirus (HPV) infections.” said Ahmad Doroudian, Chief Executive Officer of Altum. Mr Doroudian added that “ In addition to the development of topical interferon product Altum has identified other candidate drugs to create a pipeline of topical products based on the Biphasix™ technology for the treatment of pain and autoimmune diseases such as psoriasis.”


About The Biphasix™ Topical Formulation System

The Biphasix™ Topical Formulation System is a platform technology for microencapsulating therapeutic compounds in multilayered, lipid-based microvesicles. These microvesicles have complex structures that include a variety of compartments into which drug molecules can be integrated. The principal application of the technology is in the preparation of topical dosage forms for the dermal (into the skin) or mucosal (into the mucosal tissues) delivery of large molecular weight drug compounds.


About Topical Interferon Alpha-2b

Topical Interferon Alpha-2b incorporates Helix’s patented Biphasix™ drug delivery technology. It is a topical preparation that is intended to be easily self-applied to HPV-infected tissues, to deliver interferon alpha-2b into the skin and mucosal tissues.


About Altum Pharmaceuticals Inc.

Altum Pharmaceuticals Inc. is a private biopharmaceutical company engaged in clinical and commercial development of novel natural and pharmaceutical compounds, to treat cancer and autoimmune disorders. Altum focuses on development and acquisition of novel products specializing on the commercialization of existing products for cancer and diseases mediated by acute and chronic inflammatory reactions. For more information please visit the website at



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